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Reishi Primo is the world's most potent Reishi extract

Special offer on the 120 capsules package:

every second item $ 7.59 off!

Each vegetarian capsule contains 300 mg pharmaceutical grade Reishi extract.
120 caps will cover 2 months. (2 capsules daily)

  • • contains over 40 % polysaccharides ( with ≥ 90 % bioactive (1>3)(1>6) Beta-D-Glucans )
  • • contains over 5% bioactive triterpenes
  • (Click here for our supplement facts label)
No additives or fillers, certified organic, GMO-free, non-irradiated. This premium product is a 100% full-spectrum extract of wood log cultivated red Reishi fruiting bodies; 35:1 extract.

ORIVeDA Reishi Primo supplement facts label

Which medicinal mushroom is the best?

Medicinal mushrooms seem like small miracles - their therapeutic properties seem to cover almost the full spectrum of human health and well-being. And this is not exaggerated. The majority of antibiotics, several chemo-therapeutic agents, most anti-cholesterol medication (statins) and some anti-HIV medication are based on fungi. Cyclosporin, a drug without which organ transplants would be impossible, is derived from a fungus as well. And so on.

In fact, most mushrooms have only been researched for a small number of therapeutic applications. The chart below gives an indication of the existing research results of the therapeutic properties that were investigated so far.

Please take notice: 'immune balancing' covers a lot of health problems, including many allergies and auto-immune related diseases. These have not been listed separately. This overview is also not complete - we will update it and refine it when more data becomes available.

Be aware of the fact that if a property is left blank for a particular mushroom this only means that this property so far has not been investigated in depth.

overview of positive results achieved with medicinal mushroom extracts as sold by ORIVeDA

These results have all been achieved with extracted mushroom products (extraction using e.g. hot water, ethanol, methanol, fermentation or combinations of these) - they are not applicable to biomass or un-extracted, dried and powdered mushroom products or tinctures. Check our FAQ for the reason why.

free shipping worldwide

We have customers in over 85 countries. We will ship to all countries in the world, except warzones. Orders will be shipped the same day they're received, if possible.

All website orders, national and international, are shipped for free using priority-airmail, which is safe and fast.

Only for Australia, Russia, Malaysia, Israel, Indonesia, India, all South- and Central-American countries and a few others registered shipping (which includes tracking) is mandatory. The postal service can be unpredictable in these countries and orders sometimes spend over a month in transfer, if not registered and tracked. Standard priority airmail does not include tracking !! You will see the available options when checking out.

We also provide express delivery (2 - 5 working days via FedEx) to 16 non-EU countries. The costs vary between $ 20 to $ 35 for orders up to 500 grams (4 items), depending on your location.

Shipments to EU countries usually arrive within 4 - 10 working days; international shipments usually arrive within 8 - 10 working days. Due to random custom clearance procedures non-EU orders can occasionally take up to 20 working days to arrive, but this is rare.
In case you haven't received your order after 20 working days please contact us and we will investigate. Do NOT open a Paypal case, but contact us directly.

Payment and security - click here..
Wholesale prices

You are eligible for a quantity discount when you order more than 10 items, mix 'n match. You can also buy capsules and powder in bulk (MOQ: 1 kilo).

Mumijo • Shilajit and Stone Oil are excluded.
Contact us for details and the price list.

Our affiliate program - click here

Why choose Reishi ?

Science has been researching medicinal mushrooms for decades. Below we've listed the main targets in Reishi research***. For an extensive background click here  ( page opens in new window ).

  • • Immunomodulation

    A shared property of all medicinal mushrooms is said to be immune-modulation: research has been investigating their potential to normalize our natural resistance against diseases for many decades. Although undeniable proof has not yet been presented the outcome of research is promising.

    In particular water-soluble beta-glucans triggered the interest of scientists: in the EU several health-claims based on beta-glucans have been ratified in the past years by the EFSA. Beta-glucans are e.g. thought to help with immune support and with normalizing of cholesterol levels.

    Given that our immune system is the core of our health this is a very important subject - allergies, infections, auto-immune diseases and many old-age problems are all immune-related.

    Two terms are seen often in this context: adaptogenic (helping our body to adapt to the never-ending assaults on our health) and BRM (a natural Biological Response Modifier - helps to normalize the body's natural defense mechanisms without any side effects). These terms are keywords when describing medicinal mushrooms. Medicinal mushrooms do not cure or heal, but they support the body's own ability to stay healthy and perform at its best.

    Summarising in brief: the proliferation, maturation and activities of both T- and B-lympocytes, NK-cells and dendritic cells improved significantly during both lab and animal tests. Cytokine production was also triggered.

    All of these are key factors in a well functioning immune system and therefore key factors for our general health and well-being. Taking into account that our immune system is under continuous siege and that, apart from that, our immune function starts declining already around our 35th birthday an immune-supporting supplement such as Reishi can be considered a good addition to the diet.

    The beta-glucan fractions are the most important constituents for immune support. Over 90% of the polysaccharides in our Reishi extract are pure beta-glucans, a level not found in other products.

  • • Cardiovascular effects, anti-cholesterol

    The effect of Reishi on the cardiovascular system has been investigated in depth. The triterpenes present in Reishi are thought to have a normalising effect on elevated cholesterol levels, which in turn can affect high blood pressure (by reducing the potential plaque buildup in arteries). Several reports also mention a direct normalising effect on blood pressure, but more research is needed.

    Platelet aggregation decreased, probably because of the presence of trace amounts of adenosine in synergy with triterpenes. Direct and indirect lipid peroxidation (a side effect of normalised cholesterol levels) and anti-oxidant effects have been demonstrated in animal and lab experiments. All this is very promising.

  • • The effect on chronic fatigue syndrome (CFS)

    CFS is also known as ME. It is believed that ME is an auto-immune disease.

    A multicenter, double-blind, randomized, placebo-controlled trial was conducted in China. A Reishi extract was administered for 8 weeks, resulting in a reduced sense of fatigue and improved quality of life. This appears to confirm Reishi's potential effect on the immune system.

    Because the effect is balancing, there are no unwanted side effects.

  • • Anti-viral and anti-bacterial actions

    Polysaccharide-bound proteins (glycoproteins, comparable to the PSK and PSP fractions in Coriolus versicolor) from Reishi showed inhibitory effects on Herpes Simplex Virus type 1 (HSV-1), Herpes Simplex Virus type 2 (HSV-2), and Vesicular Stomatitis Virus (VSV - New Jersey strain) in a lab test. Using the plaque reduction method, a significant inhibitory effect was seen at doses that showed no cytotoxicity.

    A dried hot water extract of Reishi taken orally was used as the sole treatment for postherpetic (varicella zoster virus) neuralgia in 4 elderly patients. This treatment was reported to dramatically decrease pain and promote the healing of lesions without any toxicity, even at very high doses. This is very promising and will hopefully lead to more research in this field.

    The anti-microbial combination of Reishi with four commonly used antibiotics resulted in an additive or synergistic effect in most, but not all, instances, with apparent antagonism against cefazolin and ampicillin effects on Proteus vulgaris (known to cause urinary tract infections and wound infections).

  • • Anti-diabetic effects

    There are indications that mushroom extracts that are rich in beta-glucans can be benificial for diabetics. In several controlled animal studies the oral administration of hot water extracted Reishi was found to lower serum glucose levels. The first effects were seen after one week. The extract markedly reduced levels of phosphoenol-pyruvate carboxykinase (PEPCK).

    Serum insulin levels increased (when compared to the nontreated diabetic group) and glucose levels decreased in a dose-dependent way. Levels of non-enzymic and enzymic anti-oxidants increased and lipid peroxidation levels decreased. Therefore, in addition to its glycemic modulation, treatment with this hot water extract appeared to help to decrease oxidative stress.

    There are a few human trials with similar positive results. Overall, the data from several studies suggests that taking a Reishi extract might help in modulating blood glucose levels. However, these studies were performed mostly with animals. More support from well-planned human clinical studies is needed with and without combination with conventional medicines to be able to make more definitive claims.

  • • Liver protection, Ulcers

    Triterpenes are mainly responsible for the hepato-protective effects, but some studies also show polysaccharide/beta-glucan extracts to be benificial. A dual extract, again, would therefore be the best choice, because it will contain both triterpenes and beta-glucans. Several studies (including some with human volunteers) show a positive effect on chronic hepatitis B.

    Reishi extracts were also found to accelerate the healing of ulcers; up to 56%, depending on the dosage. The Helicobacter Pylori, the bacteria that causes e.g. peptic ulcers and gastritis (and might also be involved in the development of stomach cancers) was inhibited in its growth by a Reishi extract.

    As far as we know all research in this field has been performed with animals or it the lab, though. No controlled trials with humans exist as far as we know. Research was performed with ethanol and/or hot water extracts, which were administered orally.

  • • Anti-cancer adjuvant

    In SE-Asia Reishi extracts are popular supplements, taken by cancer patients along with conventional therapies, to reduce the side effects of those therapies (including the negative effects on the immune-function, which can lead to secondary infections and indirectly can increase the chances of metastasis). The chemo-preventive activities of the mushroom on prostate cancer were demonstrated by a triterpenoid-rich extract of Reishi that suppressed the ventral prostate growth induced by testosterone.

    Reishi appears to have a positive effect in inflammatory breast-cancer, but should not be used in hormone-related breast cancers.

    However, whether the antitumor effect of Reishi is a direct one or is mediated via the immune system is not clear. The research results with humans seem to indicate that the antitumor effects are a side effect of Reishi's effects on the immune system. Much more research with human volunteers is needed - the majority of research so far was in vivo and in vitro.

  • • Side effects, contraindications

    Some people taking high dosages of 1.5 - 9 grams per day reported one or more of the following side effects: temporary sleepiness, thirst, rashes, bloating, frequent urination and diarrhea. Taking the extract together with vitamin C seemed to improve many of the side effects. Lowering the dosage also helped.

    These reports do not give details about the quality and properties of the extracts that were consumed; and taking into account the poor quality level of most Reishi products it is not unlikely that at least some of these side effects might be related to that, so this appears not to be a direct cause for alarm.

    As said, the anti-microbial combination of Reishi with four commonly used antibiotics resulted in an additive or synergistic effect in most, but not all, instances. Reishi appears to cause cefazolin and ampicillin to be less effective against Proteus vulgaris (known to cause urinary tract infections and wound infections).

    Reishi should not be used in hormone-related breast cancers.

    Because Reishi has immune-balancing properties, it should not be used together with immune-suppressants, like those prescribed after a transplant. The blood sugar lowering effects can cause fatigue in those that are highly susceptible. In general these people are also very susceptible to e.g. caffeine and alcohol, or are diabetic. Taking the extract together with a sugar containing liquid can neutralise this effect.

    Rare side effects are: not sleeping well, bad, vivid dreams, feelings of anxiety, feeling mentally numb/clouded or having a sense of heightened mental activity. These effects are most likely caused by a genetic anomaly, like overreacting to specific triterpenes, such as lanostan.

    Lanostan triggers the function of the adrenal glands, which are responsible for adrenaline/nor-adrenaline production. If you’re very sensitive to this you can experience hyper-activity which can make you feel anxious, etc. If you experience daily stress on top of that, this will also push the production of adrenaline/noradrenaline in your body, causing anxiety.

    Reishi Primo contains a relatively high level of triterpenes; if you experience these side effects it might be better to look for a different mushroom extract or to choose a hot-water-extracted-only Reishi extract, which contains no triterpenes.

Ganoderma Lucidum, Reishi, anti-diabetic, anti-cancer adjuvant, anti-cholesterol, anti-oxidant, immune support, adaptogen

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Why choose ORIVeDA's Reishi Primo extract ?

Reishi Primo is a full-spectrum, dual extracted and highly concentrated (35 : 1) mushroom product.
We guarantee the percentages of the main bioactive compounds, optimal bioavailability and therapeutic effect.

more details..

What sets medicinal mushrooms apart from pharmaceuticals and what makes them particularly effective is the synergistic effect of the combined bioactives (mainly (1>3)(1>6)Beta-Glucans, glycoproteins and triterpenes).

In case you are interested in how ORIVeDA did its due diligence when developing Reishi Primo click here (page opens in new window).

Extraction determines the therapeutic potency, since we cannot digest non-extracted mushrooms properly.
See this -highly recommended!- link for the details about this.

Therefore extraction is essential for a therapeutic effect, and dual extraction is the best option - it will make both water-solubles and insolubles bioavailable.

Hot water extracts (incl. home made Reishi tea), tinctures and powdered products at best contain only low concentrations of bioactives and the bioavailability is a major problem - if we cannot absorb all "the good stuff" then how can we benefit from it ?

Reishi Primo is one of the very few Reishi products that actually offers all those bioactives in a bioavailable form, which guarantees the synergistic effect.

Bioavailability is guaranteed and the percentages of "the good stuff" are -verifiable- the best in the world.

Click here to see our official 'Supplement Facts' back label.

On top of that you should consider the value for money Reishi Primo is offering - unmatched, worldwide.

Reishi Primo is produced using a multi-step extraction procedure (hot water, alcohol, alcohol precipitation) which ensures a high purity product, as opposed to extraction using only hot water or a mix of water and alcohol in a single-step extraction process.

Certified and produced in compliance with ISO 9001:2008, GMP, HACCP.

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find out the positive results of research done with the mushrooms we sell
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