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CCCE stands for 'Cessante Causa, Cessat Effectus' which is Latin for 'by removing the cause you remove the effect'. It's referring to the immunological effect: if your immunity is optimal you have less chance to get sick.
CCCE® is a powerful immune-normalizing supplement, designed in particular to counter the negative effects of age and chronic stress on our immune function. CCCE® also has revitalising properties and contributes to normalizing cholesterol-levels.
The beta-glucans present in CCCE® will help to minimize the side-effects of regular medical treatment (such as chemo and radiation) and can improve the overall quality of life and our feeling of well-being by balancing and normalizing the core of our health; our immune system.
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The main bioactive compounds found in all medicinal mushroom extracts are beta-glucans (to be more specific: (1>3)(1>6) ß-D-glucans - a type of bioactive polysaccharides).
Beta-glucans give medicinal mushroom extracts their immune-modulating properties and contribute to the cholesterol-normalizing effects mushroom extracts are known for.
Three different types of very pure mushroom beta-glucan have been combined in ORIVeDA CCCE®. This increases the therapeutic bandwidth; it helps to create additional synergy and the improves the immune-modulating potential.
Beta-glucans are, simply put, long chains of molecules composed of a backbone with side-branches appearing at regular intervals, like ribs from a spine. They are very large macromolecules. The amount of branching, the intervals at which these branches appear and the molecular weight and solubility of beta-glucans are responsible for a wide array of physiological effects in both humans and animals. Our research section has a lot of background on this if you want more details.
Mushroom beta-glucan is much more bioactive than the beta-glucan found in other sources such as oats, barley and yeast. See our dedicated article for all details.
Already mentioned were (1>3)(1>6) ß-D-glucans (the numbers refer to the branching and the intervals at which these branches appear). Some mushrooms also contain (1>4)(1>6) ß-D-glucans (like the Coriolus versicolor -aka Turkey Tail-) and (1>6)(1>3) ß-D-glucans, which are only found in Maitake (Grifola frondosa).
All of these can trigger unique effects in the human immune system. In ORIVeDA CCCE® these three types have been combined into a unique synergistic formula.
Betulinic acid (found in Chaga) and proteo-glycans (such as PSP - found in Coriolus versicolor) are also important bioactives. Although the levels in this blend are not high, they might contribute to the synergy.
Cordyceps militaris contributes a significant level of cordycepin to this blend. Cordycepin is a nucleoside (3'-deoxyadenosine) that shows a variety of health effects including immunomodulatory, anti-cancer, anti-oxidant, anti-inflammatory and anti-microbial activities.
It is also a powerful revitaliser, normalizing testosteron production and stimulating the libido of both men and women.
Immunological effects of 39 mushroom supplements compared. [source]